The antiserum was produced against synthesized peptide derived from human Elk1 around the phosphorylation site of Thr417. AA range:379-428
Alternative Names:
ELK1, ETS domain-containing protein Elk-1
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012],
Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Elk1 (Phospho-Thr417) Antibody. The picture on the right is blocked with the phospho peptide.
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