Trk B (phospho Tyr706/Y707) rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number:
EBT-ES6431
Supplier Catalog Number:
ES6431
Alternative Catalog Number:
EBT-ES6431-50, EBT-ES6431-100
Manufacturer:
ELK Biotechnology
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IF, IHC
Species Reactivity:
Human, Mouse, Rat
Immunogen:
The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr706 and Tyr707. AA range:676-725
Alternative Names:
NTRK2, TRKB, BDNF/NT-3 growth factors receptor, GP145-TrkB, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk B (Phospho-Tyr706+Tyr707) Antibody. The picture on the right is blocked with the phospho peptide.
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