NIPA (phospho Ser354) rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number:
EBT-ES6527
Supplier Catalog Number:
ES6527
Alternative Catalog Number:
EBT-ES6527-50, EBT-ES6527-100
Manufacturer:
ELK Biotechnology
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, IF, WB
Species Reactivity:
Human, Monkey, Mouse, Rat
Immunogen:
The antiserum was produced against synthesized peptide derived from human NIPA around the phosphorylation site of Ser354. AA range:320-369
Alternative Names:
ZC3HC1, NIPA, HSPC216, Nuclear-interacting partner of ALK, Nuclear-interacting partner of anaplastic lymphoma kinase, hNIPA, Zinc finger C3HC-type protein 1
This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013],
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Western blot analysis of lysates from COS7 cells treated with HU 2nM 24h, using NIPA (Phospho-Ser354) Antibody. The lane on the right is blocked with the phospho peptide.
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