The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Alternative Names:
C9orf89, Bcl10-interacting CARD protein, BinCARD
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using C9orf89 Antibody. The picture on the right is blocked with the synthesized peptide.
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