Coagulation factor XIIIa, F13A, F13a1, Fibrin stabilizing factor, A subunit, Fibrinoligase, TGase, Transglutaminase A chain
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
