EBF1 (6I9) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE10271
Article Name: EBF1 (6I9) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE10271
Supplier Catalog Number: AMRe10271
Alternative Catalog Number: EKL-AMRE10271-50UL, EKL-AMRE10271-100UL, EKL-AMRE10271-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: COE1, EBF, Ebf1, O/E 1, OE1, OLF1,
Transcriptional activator which recognizes variations of the palindromic sequence 5-ATTCCCNNGGGAATT-3. Key pioneer transcription factor of B-cell specification and commitment (PubMed:27807034). Recognizes variations of the palindromic sequence 5-ATTCCCNNGGGAATT-3. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B- cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity).
Clonality: Monoclonal
Molecular Weight: 64kDa
NCBI: 1879
UniProt: Q9UH73
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: EBF1
Application Dilute: WB 1:1000-1:5000



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