Enables Wnt-protein binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within several processes, including animal organ development, negative regulation of cartilage development, and negative regulation of cell differentiation. Located in extracellular space. Is expressed in several structures, including alimentary system, central nervous system, embryo mesenchyme, genitourinary system, and skeleton. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (frizzled related protein). [provided by Alliance of Genome Resources, Apr 2022]
