Anti-BCL6 APC, Clone: [IG191E/A8], Monoclonal

Catalog Number: EXB-1A-867-T100
Article Name: Anti-BCL6 APC, Clone: [IG191E/A8], Monoclonal
Biozol Catalog Number: EXB-1A-867-T100
Supplier Catalog Number: 1A-867-T100
Alternative Catalog Number: EXB-1A-867-T100
Manufacturer: EXBIO
Category: Antikörper
Application: FC
Species Reactivity: Human, Mouse
Immunogen: pCDNA3 plasmid containing full-length sequence of human BCL6
Conjugation: APC
BCL6 is a zinc finger-containing transcription factor, which acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. On B cells, BCL6 induces proliferation, antibody class switching and affinity maturation, whereas it inhibits their differentiation into plasma cells. On T cells, BCL6 induces their differentiation into T-FH cells.
Clonality: Monoclonal
Clone Designation: [IG191E/A8]
Isotype: Mouse IgG1
Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target: BCL6
Antibody Type: Monoclonal Antibody
Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.