Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of apoptosis and autophagy, and can cross the blood-brain barrier[1][2].
Molecular Weight:
488.02
Purity:
99.85
CAS Number:
[302962-49-8]
Formula:
C22H26ClN7O2S
Target:
Apoptosis,Autophagy,Bcr-Abl,Ligands for Target Protein for PROTAC,Src
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
