LDN193189 (DM-3189) Tetrahydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].
Molecular Weight:
552.33
Purity:
99.79
CAS Number:
[2310134-98-4]
Formula:
C25H26Cl4N6
Target:
Organoid,TGF-beta Receptor
Application Notes:
MCE Product type: Reference compound
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