LDN193189 (DM-3189) hydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].
Molecular Weight:
442.94
Purity:
98.62
CAS Number:
[1062368-62-0]
Formula:
C25H23ClN6
Target:
Organoid,TGF-beta Receptor
Application Notes:
MCE Product type: Biochemical Assay Reagents
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