Apatorsen is a 2-methoxyethyl-modified antisense oligonucleotide and also a Hsp27 inhibitor. Apatorsen reduces Hsp27 mRNA and protein levels, impairs stress-induced cytoprotective functions, induces cell apoptosis, inhibits tumor growth and prevents metastasis. Apatorsen is applicable to research related to non-small cell lung cancer, castration-resistant prostate cancer, breast cancer, ovarian cancer and bladder cancer[1][2].
Molecular Weight:
7157.00
Purity:
98.54
CAS Number:
[1002331-21-6]
Formula:
C224H304N79O116P19S19
Target:
HSP
Application Notes:
MCE Product type: Oligonucleotides
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