PSMalpha3 is an inhibitor of NF-kappaB p65 and p38 MAPK. PSMalpha3 forms membrane pores and binds to residues of human insulin B chain to inhibit insulin aggregation. PSMalpha3 forms alpha-type amyloid-like fibrils to exert cytotoxic effects, and acts as a functional amyloid virulence determinant of Staphylococcus aureus. PSMalpha3 is applicable to research related to spondyloarthritis, rheumatoid arthritis, insulin-derived amyloidosis, and Staphylococcus aureus infection[1][2][3].
Molecular Weight:
2635.13
Purity:
99.39
CAS Number:
[1001405-52-2]
Formula:
C128H192N28O30S
Target:
NF-kappaB,p38 MAPK
Application Notes:
MCE Product type: Peptides
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