Angiotensin I Converting Enzyme (ACE) / CD143 Antibody, IgG2c, Clone: [ACE/3763], Mouse, Monoclonal

Catalog Number: NBT-1636-MSM3-P1
Article Name: Angiotensin I Converting Enzyme (ACE) / CD143 Antibody, IgG2c, Clone: [ACE/3763], Mouse, Monoclonal
Biozol Catalog Number: NBT-1636-MSM3-P1
Supplier Catalog Number: 1636-MSM3-P1
Alternative Catalog Number: NBT-1636-MSM3-P1-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant fragment (around aa 652-788) of human ACE/CD143 protein
Alternative Names: ACE, ACE1, angiotensin 1 converting enzyme 1, carboxycathepsin, CD143, CD143 antigen, DCP, DCP1, dipeptidyl carboxypeptidase 1, Kininase II, MVCD3, peptidase P, testicular ECA
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Clonality: Monoclonal
Clone Designation: [ACE/3763]
Molecular Weight: 150kDa
Isotype: IgG2c
NCBI: 1636
UniProt: P12821
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysi
Formalin-fixed, paraffin-embedded human small intestine stained with ACE / CD143 Mouse Monoclonal Antibody (ACE/3763).
Formalin-fixed, paraffin-embedded human small intestine stained with ACE / CD143 Mouse Monoclonal Antibody (ACE/3763).
SDS-PAGE Analysis Purified ACE / CD143 Mouse Monoclonal Antibody (ACE/3763). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of human Kidney tissue lysate using ACE / CD143 Mouse Monoclonal Antibody (ACE/3763).