This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of MCF-7 cell lysate using EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536).
Analysis of Protein Array
SDS-PAGE Analysis Purified EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of MCF-7 cell lysate using EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536).
Analysis of Protein Array containing more than 19,000 full-length human proteins using EZH2 Mouse Monoclonal Antibody (EZH2/2536). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
Flow Cytometric Analysis of PFA-fixed HeLa cells. EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).
Immunofluorescence Analysis of HeLa cells using EZH2 / KMT6 Mouse Monoclonal Antibody (EZH2/2536) followed by goat anti-mouse IgG-CF488 (green), counterstain (RedDot).
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