Recombinant fragment (around aa50-250) of human F3 protein (exact sequence is proprietary)
Alternative Names:
coagulation factor III (thromboplastin, tissue factor)
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation Factor V (Factor V, FV, proaccelerin, labile factor) is a 2,196 amino acid, single chain glycoprotein that is cleaved by Thrombin to yield an active, Ca2+-dependent dimer that is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates into a prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Tissue factor (TF), also designated coagulation Factor III) is a cell surface glycoprotein that enables cells to initiate blood coagulation cascades. It functions as a high-affinity receptor for coagulation Factor VII.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified CD142 Mouse Monoclonal Antibody (CD142/9196). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of Human Brain, Human Heart and A431 lysates using CD142 Mouse Monoclonal Antibody (CD142/9196).
Western Blot Analysis of A-431 lysate using CD142 Mouse Monoclonal Antibody (CD142/9196).
Formalin-fixed, paraffin-embedded human lung stained with CD142 Mouse Monoclonal Antibody (CD142/9196). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human lung stained with CD142 Mouse Monoclonal Antibody (CD142/9196). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
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