Human recombinant FABP1 protein fragment (around aa1-127) (exact sequence is proprietary)
Alternative Names:
FABP1, L-FABP
Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human kidney stained with FABP1 Mouse Monoclonal Antibody (FABP1/3940).
Formalin-fixed, paraffin-embedded human kidney stained with FABP1 Mouse Monoclonal Antibody (FABP1/3940).
SDS-PAGE Analysis Purified FABP1 Mouse Monoclonal Antibody (FABP1/3940).Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of human kidney tissue lysate using FABP1 Mouse Monoclonal Antibody (FABP1/3940).
Analysis of Protein Array containing more than 19,000 full-length human proteins using Monospecific to FABP1 Mouse Monoclonal Antibody (FABP1/3940). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
* VAT and and shipping costs not included. Errors and price changes excepted
