Recombinant Ferritin, Light Chain (FTL) (Microglia Marker) Antibody, Clone: [FTL/2338R], Rabbit, Monoclonal

Article Name:	Recombinant Ferritin, Light Chain (FTL) (Microglia Marker) Antibody, Clone: [FTL/2338R], Rabbit, Monoclonal
Biozol Catalog Number:	NBT-2512-RBM5-P0
Supplier Catalog Number:	2512-RBM5-P0
Alternative Catalog Number:	NBT-2512-RBM5-P0-20,NBT-2512-RBM5-P0-100
Manufacturer:	NeoBiotechnologies
Host:	Rabbit
Category:	Antikörper
Application:	IHC, WB
Species Reactivity:	Guinea pig, Hamster, Human, Mouse, Rabbit, Rat
Immunogen:	Recombinant human FTL protein fragment (around aa 38-165) (exact sequence is proprietary)
Alternative Names:	Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Clonality:	Monoclonal
Clone Designation:	[FTL/2338R]
Molecular Weight:	19-25kDa
NCBI:	2512
UniProt:	P02792
Form:	200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:	Recombinant Monoclonal Antibody

Application Notes:

Western Blot (1-2ug/ml),Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes)


	Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
	SDS-PAGE Analysis of Purified Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R). Confirmation of Purity and Integrity of Antibody.
	Western Blot Analysis of human HeLa cell lysate using Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
	Western Blot Analysis of human kidney tissue lysate using Ferritin LC Rabbit Recombinant Monoclonal Antibody (FTL/2338R).
	Western Blot Analysis of Human Liver, Mouse Liver, Rat Liver, Hamster Liver, Guinea pig Liver, Rabbit Liver, Human Kidney, Mouse Kidney, Rat Kidney, Hamster Kidney, Guinea pig Kidney, Rabbit Kidney, Human Spleen, Mouse Spleen, Rat Spleen, Hamster Spleen, Guinea pig Spleen and Rabbit Spleen tissue lysates using Ferritin Light Chain Recombinant Rabbit Monoclonal Antibody (FTL/2338R).
	Western Blot Analysis of Human Brain, Human Kidney, Human Liver, Human Lung, Human Spleen, A431, and HeLa lysates using Ferritin Light Chain Recombinant Rabbit Monoclonal Antibody (FTL/2338R).