PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of HDLM-2 cell lysate using CD274 Rabbit Recombinant Monoclonal Antibody (PDL1/8222R).
Western Blot Analysis of Human Kidney, Human Lung and Raji lysate using CD274 Rabbit Recombinant Monoclonal Antibody (PDL1/8222R).
