Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 min
Formalin-fixed, paraff
Formalin-fixed, paraffin-embedded human Placenta stained with Glycophorin A Mouse Monoclonal Antibody (GYPA/280).
Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Glycophorin A Mouse Monoclonal Antibody (GYPA/280).
Formalin-fixed, paraffin-embedded human Angiosarcoma stained with Glycophorin A Mouse Monoclonal Antibody (GYPA/280).
SDS-PAGE Analysis Purified Glycophorin A Mouse Monoclonal Antibody (GYPA/280). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of K562 cell lysate usingGlycophorin A Mouse Monoclonal Antibody (GYPA/280).
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