Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-419 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
SDS-PAGE Analysis of Purified HSP60 Mouse Monoclonal Antibody (LK2) Confirm
Immunofluorescence staining of MEOH-fixed HeLa cells using HSP60 Mouse Monoclonal Antibody (LK2) followed by goat anti-mouse IgG-CF488 (green), nuclei labeled with NucSpot (red).
SDS-PAGE Analysis of Purified HSP60 Mouse Monoclonal Antibody (LK2) Confirmation of Integrity and Purity of Antibody.
Western blot analysis of Hep2 cell lysate using HSP60 Mouse Monoclonal Antibody (LK2).
Formalin-fixed, paraffin-embedded human liver in colon stained with HSP60 Mouse Monoclonal Antibody (LK2).
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