Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal diluti
Formalin-fixed, paraffin-embedded human spleen stained with
Formalin-fixed, paraffin-embedded human spleen stained with Lambda Light Chain Recombinant Rabbit Monoclonal (LLC/3774R). Inset: PBS instead of primary antibody, secondary only negative control.
Formalin-fixed, paraffin-embedded human spleen stained with Lambda Light Chain Recombinant Rabbit Monoclonal (LLC/3774R).
Formalin-fixed, paraffin-embedded human spleen stained with Lambda Light Chain Recombinant Rabbit Monoclonal (LLC/3774R).
Western Blot Analysis of Spleen tissue lysates of different species using Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3774R).
Western Blot Analysis of Human Serum and Human Spleen tissue lysates using Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (LLC/3774R).
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