A synthetic peptide from the C-terminus of human LGALS3 protein (aa 150-200) (exact sequence is proprietary)
Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. OOGalectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation OOof benign and malignant thyroid neoplasms. OOGalectin-3 may also be useful in the identification of certain liver disorders.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of MCF-7 lysate using Galectin-3 Mouse Monoclonal Antibody (LGALS3/6583)
Western Blot Analysis of Human Colon and Heart tissue lysate using LGALS3 Mouse Monoclonal Antibody (LGALS3/6583).
Western Blot Analysis of Human Heart, Mouse Heart, Rat Heart, MCF7 lysates using LGALS3 Mouse Monoclonal Antibody (LGALS3/6583).
Formalin-fixed, paraffin-embedded human skin stained with Galectin-3 Mouse Monoclonal Antibody (LGALS3/6583). Inset: PBS instead of primary antibody, secondary only negative control.
Formalin-fixed, paraffin-embedded human prostate stained with Galectin-3 Mouse Monoclonal Antibody (LGALS3/6583). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified Galectin-3 Mouse Monoclonal Antibody (LGALS3/6583). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using Galectin-3-Monospecific Mouse Monoclonal Antibody (LGALS3/6583). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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