Bovine, Canine, Feline, Gallus, Guinea pig, Human, Porcine, Rabbit, Rat
Immunogen:
Recombinant full-length human MYH11 protein
Alternative Names:
AAT4, Myosin heavy chain 11 (MYH11), Myosin heavy chain 11 smooth muscle, Smooth muscle myosin heavy chain 11, Myosin-11, SM1, SM2, SMHC, SMMHC
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution f
SDS-PAGE Analysis of Purified SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R). Confirmation of Integrity and Purity of the Antibody.
Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).
Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).
Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).
Western blot analysis of Human Intestine, Mouse Intestine, Rat Intestine, Hamster Intestine, Guinea pig Intestine, Rabbit Intestine, Human Stomach, Mouse Stomach, Rat Stomach, Hamster Stomach, Guinea pig Stomach and Rabbit Stomach tissue lysates using Myosin Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).
Western Blot Analysis of Human Intestine and Human Stomach tissue lysates using SM-MHC Rabbit Recombinant Monoclonal Antibody (MYH11/2303R).
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