Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 2
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Formalin-fixed, paraffin-embedded human Prostate stained with ODC1 Rabbit Recombinant Monoclonal Antibody (ODC1/2878R).
SDS-PAGE Analysis of Purified ODC1 Rabbit Recombinant Monoclonal Ab (ODC1/2878R). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of PC3 cell lysate usingODC1 Rabbit Recombinant Monoclonal Antibody (ODC1/2878R).
Western Blot Analysis of Human Liver and HepG2 lysates using Ornithine Decarboxylase-1 Recombinant Rabbit Monoclonal Antibody (ODC1/2878R).
Western Blot Analysis of Liver tissue lysate of different species using Ornithine Decarboxylase-1 Recombinant Rabbit Monoclonal Antibody (ODC1/2878R).
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