BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow Cytometry (1-2ug/million cells), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95
Western Blot of HepG2 cell lysate using BCL10 Mouse Monoclonal Antibody (BL10/411).
SDS-PAGE Analysis of Purified BCL10 Mouse Monoclonal Antibody (BL1
Formalin-fixed, paraffin-embedded human Tonsil stained with BCL10 Mouse Monoclonal Antibody (BL10/411).
Western Blot of HepG2 cell lysate using BCL10 Mouse Monoclonal Antibody (BL10/411).
SDS-PAGE Analysis of Purified BCL10 Mouse Monoclonal Antibody (BL10/411). Confirmation of Purity and Integrity of Antibody.
Flow Cytometric Analysis of PFA-fixed K562 cells using BCL10 Mouse Monoclonal Antibody (BL10/411) followed by Goat anti-Mouse IgG-CF488 (Blue), Isotype Control (Red)
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