Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen
This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
ELISA (For coating, order antibody without BSA), ,Functional Studies, ,Flow Cytometry (1-2ug/million cells), ,Immunofluorescence (1-2ug/ml), ,Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified CD47 Mouse Monoclonal Antibody (IAP/964)
Immunofluorescence Analysis of PFA-fixed MCF-7 cells. CD47 Mouse Monoclonal Antibody (IAP/964) followed by goat anti-mouse IgG-CF488 (green). The nuclear counterstain is RedDot (red).
SDS-PAGE Analysis of Purified CD47 Mouse Monoclonal Antibody (IAP/964) Confirmation of Integrity and Purity of Antibody.
Immunofluorescence Analysis of live Jurkat cells. CD47 Mouse Monoclonal Antibody (IAP/964) followed by goat anti-mouse IgG-CF488 (green). The nuclear counterstain is RedDot.
Flow cytometric analysis of live Jurkat cells. CD47 Mouse Monoclonal Antibody (IAP/964) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).
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