A portion of amino acids 479-508 from the human protein was used as the immunogen for this anti-PCSK9 antibody.
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
Western blot: 1:1000,IHC (Paraffin): 1:10-1:100,Flow Cytometry: 1:10-1:50
Application Notes:
The stated application concentrations are suggested starting points. Titration of the anti-PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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