This HuR antibody was produced from rabbits immunized with human ELAVL1/HuR recombinant protein.
ELAVL1/HuR is involved in 3-UTR ARE-mediated MYC stabilization. It binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.
