CFP Antibody / Complement Factor P / Properdin, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-F52012-0.08ML
Supplier Catalog Number:
F52012-0.08ML
Alternative Catalog Number:
NSJ-F52012-0.08ML
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, FACS, WB
Species Reactivity:
Human
Immunogen:
A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
