SUZ12 Antibody / Suppressor of zeste 12 protein homolog, Rabbit, Polyclonal

Catalog Number: NSJ-F52128-0.4ML
Article Name: SUZ12 Antibody / Suppressor of zeste 12 protein homolog, Rabbit, Polyclonal
Biozol Catalog Number: NSJ-F52128-0.4ML
Supplier Catalog Number: F52128-0.4ML
Alternative Catalog Number: NSJ-F52128-0.4ML
Manufacturer: NSJ Bioreagents
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human, Mouse
Immunogen: A portion of amino acids 559-588 from the human protein was used as the immunogen for this SUZ12 antibody.
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Clonality: Polyclonal
UniProt: Q15022
Purity: Antigen affinity
Form: In 1X PBS, pH 7.4, with 0.09% sodium azide
Antibody Type: Primary Antibody
Application Dilute: Western blot: 1:1000
Application Notes: Titration of the SUZ12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.