This CB1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 433-468 amino acids from the C-terminal region of human Cannabinoid receptor 1.
Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.