This SPHK2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 52-84 amino acids from the N-terminal region of human SPHK2.
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- dihydrosphingosine, D-erythro-sphingosine and L-threo- dihydrosphingosine. Binds phosphoinositides.
