A portion of amino acids 78-107 from the human protein was used as the immunogen for the LXN antibody.
Latexin possesses nearly irreversible, non-competitive and potent inhibition of zinc-dependent metallocarboxypeptidases CPA1, CPA2, and CPA4. It is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Latexin plays a role in regional specification and/or morphogenesis of the forebrain.
The stated application concentrations are suggested starting points. Titration of the LXN antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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