A portion of amino acids 470-504 from the human protein was used as the immunogen for the Erythropoietin Receptor antibody.
Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Western blot: 1:500-1:2000,Flow cytometry: 1:25 (1x10e6 cells)
Application Notes:
The stated application concentrations are suggested starting points. Titration of the Erythropoietin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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