A portion of amino acids 70-98 from the human protein was used as the immunogen for the CFL1 antibody.
Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
The stated application concentrations are suggested starting points. Titration of the CFL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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