A portion of amino acids 1-200 of the human protein was used as the immunogen for the HSD17B13 antibody.
Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
