A recombinant human partial protein (amino acids 155-254) was used as the immunogen for this BARX1 antibody.
BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.
Clonality:
Monoclonal
Clone Designation:
[BARX1/2759]
UniProt:
Q9HU1
Purity:
Protein G affinity chromatography
Form:
1 mg/ml in 1X PBS, BSA free, sodium azide free
Antibody Type:
Primary Antibody
Application Dilute:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Notes:
Optimal dilution of the BARX1 antibody should be determined by the researcher.
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