Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this Herpes Virus 8 antibody.
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposis sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castlemans disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
Clonality:
Monoclonal
Clone Designation:
[HHV8/3606]
Purity:
Protein G affinity chromatography
Form:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Antibody Type:
Primary Antibody
Application Dilute:
ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml
Application Notes:
Optimal dilution of the Herpes Virus 8 antibody should be determined by the researcher.
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