HHV8 Antibody / Herpes Virus 8, Clone: [LN53], Rat, Monoclonal
Biozol Catalog Number:
NSJ-V8345SAF-100UG
Supplier Catalog Number:
V8345SAF-100UG
Alternative Catalog Number:
NSJ-V8345SAF-100UG
Manufacturer:
NSJ Bioreagents
Host:
Rat
Category:
Antikörper
Application:
ELISA, IF, IHC-P
Species Reactivity:
Virus
Immunogen:
Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 was used as the immunogen for this HHV8 antibody.
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposis sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castlemans disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
