IL-10RA Antibody / IL-10R1, Clone: [1B1.3a], Rat, Monoclonal
Biozol Catalog Number:
NSJ-V8346-20UG
Supplier Catalog Number:
V8346-20UG
Alternative Catalog Number:
NSJ-V8346-20UG
Manufacturer:
NSJ Bioreagents
Host:
Rat
Category:
Antikörper
Application:
FACS
Species Reactivity:
Mouse
Immunogen:
Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.
This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.
