Recombinant Chromogranin A Antibody, Clone: [CHGA/4544R], Rabbit, Monoclonal
Biozol Catalog Number:
NSJ-V8371-20UG
Supplier Catalog Number:
V8371-20UG
Alternative Catalog Number:
NSJ-V8371-20UG
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
IHC-P
Species Reactivity:
Human
Immunogen:
A portion of amino acids 400-600 from the human protein was used as the immunogen for the recombinant Chromogranin A antibody.
Chromogranin A (CGA) is an acidic protein which is reported to be widely expressed in neural tissues and in secretory granules of human endocrine cells e.g. parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas and C cells of the thyroid. GA is found in the large majority of epithelial NE tumors: pituitary adenomas, parathyroid and pancreatic islet cell tumors, medullary thyroid carcinoma, and carcinoid tumors. Together with synaptophysin, CGA is the most important marker for the identification of NE and neuronal tumors and NE/neuronal differentiation in other tumors.
