Purified human beta 1 integrin from HT1080 fibrosarcoma cells was used as the immunogen for the ITGB1 antibody.
CD29/Integrin beta 1/ITGB1 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin.
