Integrin alpha V + beta 6 Antibody, Clone: [AvB6 53a.2], Rat, Monoclonal
Biozol Catalog Number:
NSJ-V8494-20UG
Supplier Catalog Number:
V8494-20UG
Alternative Catalog Number:
NSJ-V8494-20UG
Manufacturer:
NSJ Bioreagents
Host:
Rat
Category:
Antikörper
Application:
FACS, IF, IP, WB
Species Reactivity:
Human
Immunogen:
Mouse fibroblasts retrovirally infected with cDNA to express a mouse/human avb6 chimera was used as the immunogen for the Integrin alpha V + beta 6 antibody.
Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.