RAF-IN-1 is a potent inhibitor of b/cRAF, acting on cRAF (IC50: 3.8 nM), bRAFwt (IC50: 36 nM), bRAFV600E (IC50: 29.4 nM) and inhibiting A375 and H358 cell lines carrying the bRAFV600E mutation with a GI50 of 3.4 and 2.9 nM.
Molecular Weight:
497.47
Purity:
99.62%
CAS Number:
[2695505-82-7]
Formula:
C26H22F3N3O4
Target:
Raf
T63365
T63365
* VAT and and shipping costs not included. Errors and price changes excepted
