NPBA is a bifunctional small molecule that acts as both an agonist of the potassium ion-gated double-porin channel TASK-3 (KCNK9) and an antagonist of the tandem-porin weak inwardly rectifying potassium channel TWIK2. NPBA significantly inhibits the activation of the NLRP3 inflammasome in macrophages.
Molecular Weight:
353.3
Purity:
99.90%
CAS Number:
[524033-40-7]
Formula:
C16H14F3N3O3
Target:
Potassium Channel
T84683
T84683
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