SN-38-D3 is a deuterated form of SN-38. As the active metabolite of the topoisomerase I (TopoisomeraseI) inhibitor irinotecan, SN-38 (T1703) (NK012) notably inhibits the synthesis of DNA and RNA, with IC50 values of 0.077 and 1.3 µM, respectively.
Molecular Weight:
395.42
CAS Number:
[718612-49-8]
Formula:
C22H20N2O5
Target:
ADC Cytotoxin
T89645
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