Isoforretin A, CAS [[2231757-68-7]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T89898
Supplier Catalog Number:
T89898
Alternative Catalog Number:
TGM-T89898-10MG,TGM-T89898-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Alternative Names:
IsoA
Isoforretin A is a potent inhibitor of thioredoxin-1 (Trx1) with significant biological activity, inducing anti-tumor effects mediated by reactive oxygen species (ROS). The compound inhibits Trx1 activity by covalently binding to the activation site residues Cys32/Cys35, which triggers ROS accumulation, leading to DNA damage and apoptosis (Apoptosis) in cancer cells. Additionally, Isoforretin A has demonstrated the ability to suppress the growth of HepG2 tumors in a mouse hepatic cell carcinoma xenograft model.
Molecular Weight:
534.6
CAS Number:
[2231757-68-7]
Formula:
C28H38O10
Target:
Reactive Oxygen Species|||Apoptosis
T89898
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