BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 µM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates beta-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-kappaB). It disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association
Molecular Weight:
309.18
Purity:
95%
CAS Number:
[304456-62-0]
Formula:
C12H9BrN2OS
Target:
c-Myc|||NF-kappaB
T9033
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