TACSTD2, Recombinant, Human, aa31-274, His-Tag (Tumor-associated Calcium Signal Transducer 2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2)
Catalog Number:
USB-377982
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| Article Name: | TACSTD2, Recombinant, Human, aa31-274, His-Tag (Tumor-associated Calcium Signal Transducer 2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2) |
| Biozol Catalog Number: | USB-377982 |
| Supplier Catalog Number: | 377982 |
| Alternative Catalog Number: | USB-377982-50,USB-377982-250 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| TACSTD2, also known as tumor-associated calcium signal transducer 2, is an identified cell surface glycoprotein highly expressed by human carcinomas. It is detected in normal kidney, lung, ovary and testis, similarly to the human gene. It is undetectable in undifferentiated spindle cell carcinomas, this suggests a preferential expression at early stages of tumor progression. Its inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway. Source: Recombinant protein corresponding to aa31-274 from human TACSTD2, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~28.6kD (253aa), 28-40kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) Amino Acid Sequence: ADPQDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLTHHH HHH Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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